BioWorld

New AChE inhibitor has neuroprotective and anti-amyloidogenic effects

Researchers from Anhui Medical University (AMU) and Wuhan University of Technology (WUT) presented the discovery of novel acetylcholinesterase (AChE) inhibitors as potential disease-modifying ...
BioWorld

Discovery of MJM-255, a potent AChE inhibitor for the treatment of Alzheimer’s disease

Researchers from the University of Santiago de Compostela and University of Porto have reported the discovery of a novel acetylcholinesterase (AChE) inhibitor, MJM-255, being developed for the ...
Medscape

Off-Label Use of Dementia Meds Tied to Lower Mortality in DLB

Off-label use of antidementia agents by patients with dementia with Lewy bodies (DLB) is linked to lower mortality, new research suggests. Investigators found that among patients with DLB who used ...
Healthline

Is Aricept an Antipsychotic Drug?

Aricept (donepezil) is a prescription drug used to treat dementia related to Alzheimer’s disease. Aricept belongs to a class of drugs called acetylcholinesterase inhibitors. It is not an antipsychotic ...
Nature

Alzheimer's Disease Research and Cholinesterase Inhibition

Alzheimer's disease (AD) remains a foremost challenge in neurodegenerative research, with cholinesterase inhibition representing a pivotal mechanism in symptomatic treatment. Inhibitors of ...
EurekAlert!

For people with dementia with Lewy bodies, treatment with acetylcholinesterase inhibitors, with or without memantine treatment, appears to be associated with both lower risk of ...

In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine: http://journals.plos.org/plosmedicine/article?id=10.1371 ...