Cyclooxygenase (COX) is the rate-limiting enzyme of prostanoid biosynthesis and ubiquitously found in most cells including microvascular endothelium and vascular smooth muscle (VSM). COX has two major ...

Some fundamental features of extracellular volume overload in heart failure have been known and well documented in medical literature for decades. At the turn of the century, Starling [1] noted that ...

Neuronal activity is thought to communicate to arterioles in the brain through astrocytic calcium (Ca²⁺) signaling to cause local vasodilation. Paradoxically, this communication may cause ...

In this arteriolar niche, breast cancer stem cells and arteriolar endothelial cells cross-talk using a well-known signaling pathway. Targeting this pathway may offer therapeutic potential BIRMINGHAM, ...

Eclampsia is a dreaded complication of pregnancy. Its incidence varies according to economic, geographic, and social factors. Improved prenatal care has decreased the overall incidence of eclampsia ...