As compared with BA.2, the BA.2.12.1 subvariant has substitutions L452Q and S704L in its spike protein, and both BA.4 and BA.5 have additional changes. Substitutions L452Q, L452R, and F486V are in the ...
Since the COVID-19 pandemic began, health officials have warned that the biggest barrier to controlling the virus would be its ability to mutate into ever more infectious and dangerous forms. The ...
Therefore, we collected serum samples from participants who had received three doses of either of the original monovalent mRNA vaccines followed by one dose of a bivalent vaccine targeting BA.4–BA.5 ...
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