Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

DNA methylation in bacteria, primarily involving the addition of methyl groups to adenine or cytosine residues, constitutes a pivotal epigenetic mechanism that modulates gene expression without ...

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation. Bacterial infections cause millions of deaths each year, with the global threat ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 40 (October 4, 2022), pp. 1-9 (9 pages) Horizontal gene transfer drives bacterial evolution. To confer ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

Washington, D.C. – A new study, “Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein” published in Biochemistry, provides key insights into how bacterial cAMP receptor ...

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs. An international collaboration has ...

Some genetic disorders—such as cystic fibrosis, hemophilia and Tay Sachs disease—involve many mutations in a person's genome, ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...