Nucleic acids are fundamental biomacromolecules that not only store and transmit genetic information but also regulate myriad biochemical processes essential for maintaining cellular homeostasis. In ...

The interior of a cell is packed with proteins and nucleic acids, such as RNA, all of which need to perform specific ...

Ocular fluids provide a window into the health of the eye and the development of various pathologies. However, their study ...

A continuation of CHEM.4500 with emphasis on metabolic pathways of amino acids and nucleic acid, biosynthesis of proteins and selected topics in molecular biology and various areas of biochemistry.

Some biologists have long hoped that small pieces of RNA that silence genes could help wipe out genetic diseases. But developing nucleic acid medications with good drug properties, such as selectivity ...

In advancing our knowledge of life at the molecular level and has significant implications for various scientific and practical applications.

Can chemists synthesize life? Not quite yet. But famed Biochemist Gerhard Schramm of the Max Planck Institute for Virus Research at Tubingen, Germany, is coming remarkably close. Last month he told a ...

Carolyn Bertozzi and colleagues laid out a way to make paradigm-shifting "click-chemistry" compatible with living cells, ...

So far as is known today, uric acid serves no biochemical function in the body other than being an end product of purine metabolism. The metabolically important purines, adenine and guanine, serve as ...