Decoding the T cell burst: Signature genes predict T cell expansion in cancer immunotherapy

The ability of immune cells—particularly CD8+ T cells—to launch a rapid burst of proliferation inside tumors is key to the ...
The Scientist

Tumor Cell “Pockets” May Signal Immunotherapy Success

Research shows CRATERs correlate with immunotherapy success, boosting CD8+ T cells in melanoma. Find out how this discovery ...
ascopubs.org

CD8+ T Cells in Cutaneous T-Cell Lymphoma: Expression of Cytotoxic Proteins, Fas Ligand, and Killing Inhibitory Receptors and Their Relationship With Clinical Behavior

PURPOSE: We investigated the number, phenotype, and prognostic significance of CD8+ T cells in patients with mycosis fungoides (MF) and CD30− primary cutaneous large T-cell lymphoma (PCLTCL). PATIENTS ...

AbbVie: "Strong Buy" On Rinvoq Expansions And Immunology Pipeline Addition

I rate AbbVie stock as a Strong Buy, based on its FDA approval of Rinvoq. Read the latest analysis on the stock here.
ALZFORUM

A Tale of Two T Cells—Slowing Tau Spread, Shredding White Matter

Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...
Verywell Health on MSN

What Does Cytotoxic Mean?

Medically reviewed by Sanja Jelic, MD Key Takeaways Cytotoxic substances can harm or kill cells and are used in chemotherapy ...

Scientists create nanoparticle vaccine that prevents cancer

In a breakthrough that could potentially rewrite the prevention and treatment of cancer, scientists have discovered how ...
ascopubs.org

Efficacy of Immune Checkpoint Inhibition and Cytotoxic Chemotherapy in Mismatch Repair-Deficient and Microsatellite Instability-High Pancreatic Cancer: Mayo Clinic Experience

Pancreatic cancer (PC) carries a poor prognosis with high rates of unresectable/metastatic disease at diagnosis, recurrence after resection, and few systemic therapy ...