Thomas J. Hund, Ph.D., post-doctoral researcher in Pathology ( in Dr. Jeffrey Saffitz laboratory) at the Washington University School of Medicine, and Yoram Rudy, The Fred Saigh Distinguished ...
To identify antagonists of canonical Wnt signaling, we used a cell-based TOPflash reporter system to screen the Gen-plus drug library (Microsource) that contains 960 FDA-approved drugs. In this system ...
It is vital to the regulation of cell activities through its role as a second messenger. Calcium signaling is the process whereby low cytoplasmic concentrations are deliberately increased to activate ...
Radiation Research, Vol. 165, No. 4 (Apr., 2006), pp. 400-409 (10 pages) Much evidence now exists regarding radiation-induced bystander effects, but the mechanisms involved in the transduction of the ...
Environmental stimuli such as UV, pathogen attack, and gravity can induce rapid changes in hydrogen peroxide (H2O 2) levels, leading to a variety of physiological responses in plants. Catalase, which ...
Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...
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