Cell-free protein synthesis (CFPS) represents a transformative technology in which the molecular machinery of transcription and translation is extracted from living cells and employed in a controlled ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound.

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

A group of natural compounds attracting attention for their anti-aging potential has a dark side. New research shows how a ...

Proteins of all sizes and shapes do most of the work in living cells, and the DNA sequences in genes spell out the instructions for making those proteins. The crucial job of reading the genetic ...

Galit Meshulam-Simon is the associate director of Commercial Applications at Elegen. COVID-19 brought messenger RNA (mRNA) into the global spotlight, demonstrating its speed, flexibility, and efficacy ...

Scientists developed a new mRNA platform that keeps vaccines and therapies effective in older adults and patients with obesity, where current treatments often lose potency.

Scientists have identified a critical breakdown in the cellular machinery that produces proteins in aging brains.

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...