In what might be a surprise for some, the male sex chromosome is far more complex than its female counterpart. This is why it’s taken scientists so long to work out exactly what makes a male a male.

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...

Two decades after the human genome sequence was completed, researchers have finally finished a map of the piece that makes males distinct. The Y chromosome is what distinguishes biological males from ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

The chromosome associated with male development, which is the last mysterious piece of the human genome, has been fully sequenced by a team of more than 100 researchers around the world, including ...

The Y chromosome is perhaps the most puzzling part of the human genome. Associated with male development, it is chock-full of repetitive and inverted stretches of DNA, a hurdle that makes it ...

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and demonstrated partial molecular correction using antisense oligonucleotides.

Genes are segments of DNA (deoxyribonucleic acid) that are located inside every human cell. The DNA inside each cell is tightly coiled in structures called chromosomes. Each chromosome contains a ...