Researchers have solved the X-ray crystal structure of the enzyme that makes obafluorin -- a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria. This new class of ...
As humans do not synthesize dTDP-l-rhamnose, the four enzymes of its metabolic pathway represent very appealing targets against which new drugs might be designed. Analysis of V. cholerae mutants with ...
Natural products derived from microorganisms are a promising source of new active ingredients, but are often produced only in ...
One of the most revolutionary discoveries of the century, the CRISPR gene-editing system is built on a bacterial defense mechanism that allows scientists to make precise edits to DNA. Now scientists ...
ST. LOUIS--(BUSINESS WIRE)--M6P Therapeutics (“M6PT” or “the Company”), a privately held life sciences company developing next-generation recombinant enzyme and gene therapies for lysosomal storage ...
An enzyme known as Lp-PLA2 boosts the risk of stroke and early death, perhaps as much as high blood pressure or bad cholesterol, according to a pair of top scientists at Cambridge University. And ...
Study in fission yeast revealed a key role for a set of enzymes called agmatinases, which break down the metabolite agmatine into polyamines.
Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a ...
Scientists in the U.S. and Italy have discovered that fragments of the stomach enzyme pepsinogen, which when activated normally help to digest proteins in our food, also have antibiotic activity that ...
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