Clonal evolution begins before the development of neoplasia in IBD, accelerated by repeated cycles of epithelial wounding and repair. Here, the authors summarize the biological drivers of mutant clone ...
AI-based predictive tool for detection of ctDNA in pancreatic adenocarcinoma using nationwide comprehensive genomic profiling data. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I ...
Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...
Using lung cancer biospecimens from the Sherlock-Lung study, an international team led by National Institutes of Health (NIH) researchers, identified key factors that drive tumor evolution and ...
About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called ...