Scientists first observed the biological phenomenon of restriction and modification in the 1950s, but they did not identify and isolate restriction enzymes until the late 1960s. 3 In 1970, Hamilton ...

Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

In a recent letter published in Nature Aging, researchers assessed the impact of caloric restriction (CR) on biological aging among the comprehensive assessment of the long-term effects of reducing ...

Research from the Reik lab at the Babraham Institute has advanced our understanding of the role of DNA methylation during the earlier stages of development. Technological advances in this field, ...

Scientists have figured out how to modify CRISPR’s basic architecture to extend its reach beyond the genome and into what’s known as the epigenome – proteins and small molecules that latch onto DNA ...

BOULDER, Colo.--(BUSINESS WIRE)--Watchmaker Genomics, a supplier of innovative products for molecular analysis, today announced a multi-year, co-exclusive agreement with Exact Sciences Corporation, a ...

To many working biologists, DNA-modifying enzymes are tools, not unlike a pair of molecule-sized scissors. To Dr. Barry Stoddard, a professor in the Basic Sciences division at Fred Hutch, these ...

In vitro findings reveal Telomir-1's dual action: targeting DNA methylation switches and cutting into the Wnt "fuel line" that drives cancer growth. MIAMI, FLORIDA / ACCESS Newswire / August 28, 2025 ...

In a first of its kind randomized controlled trial an international team of researchers shows that caloric restriction can slow the pace of aging in healthy adults. The CALERIE™ intervention slowed ...