A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...
Potential first-in-class, and industry-leading DNA polymerase Theta (Polθ) inhibitor, ART6043 demonstrated an attractive tolerability profile, expected PK/PD activity, and promising clinical ...
Known as a DNA polymerase, this enzyme binds with successive nucleotides in a length of DNA and generates a complimentary chain of nucleotides, one by one. This versatile nanomachine is used in living ...
Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could ...
DURHAM, N.C. -- Biochemists have performed detailed structural studies that reveal for the first time how an enzyme key to DNA replication stalls when an error occurs ...
Researchers have found new ways to string together artificial DNA bases. The techniques could aid the creation of altered genetic material for applications in medicine and technology. Floyd Romesberg ...
Artios Pharma Limited (“Artios”), a biopharmaceutical company committed to realizing the therapeutic power of targeting the ...
Enzymes evolved to work with DNA accept a cheap imitation, say US researchers. DNA polymerase, that copies chromosomes before a cell divides, will duplicate a synthetic molecule called threose nucleic ...
There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...
Sometimes a replicating cell must choose the lesser of two evils. For example, when a replicating cell is stressed, it may struggle to pair bases against its single-stranded DNA (ssDNA) template, even ...
Has the next biotech unicorn just been minted? Two California firms are focused on a radical new way of writing DNA to create everything from COVID-19 antibodies to new options for high-density data ...
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