So-called junk DNA was given that unfortunate nickname because its function was so mysterious. These vast regions of the genome do not code for protein and are made up of highly repetitive sequences.

Researchers use long-read genome sequencing to discover 33% more structural variants and 38% more tandem repeats linked to autism spectrum disorder.

Long-read genome sequencing reveals autism gene variants and structural changes, helping explain missing heritability and advancing precision diagnostics.

Tandem repeats are segments of DNA in which short nucleotide motifs are repeated in contiguous blocks. These repeated sequences—particularly short tandem repeats (STRs) composed of 1–6 base pair ...

CHAPEL HILL, NC – In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA ...

A research team has built a genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis ...

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA coded in the base of ...

There is evidence that tandem repeat sequences (TRS) could have essential roles in cell functioning processes. We aimed to detect and describe minisatellites contained in the sequences of a cDNA ...

Using state-of-the-art whole-genome sequencing and machine learning techniques, researchers conducted one of the first and the largest investigations of tandem repeats in schizophrenia, elucidating ...