Edited by B Jordan Springer-Verlag, Heidelberg. 2001; 140 pp. £30.00, paperback. ISBN 3-540-41508-4. The heady euphoria of the late nineties, promising that DNA microarrays would be ubiquitous tools ...
Pat Brown, CEO of Impossible Foods (CA, USA) and professor emeritus in the department of biochemistry at Stanford University (CA, USA), takes us through the invention of DNA microarrays, their ...
Based on electrostatic repulsion — in which objects with the same electrical charge repel one another — the technique is relatively simple and inexpensive to implement, and can be carried out in a ...
In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...
Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...
DNA microarray chips enable the parallel investigation of a given sample concerning the presence and amount of specific DNA sequences within that sample. Whereas today such chips utilize optical ...
This is a preview. Log in through your library . Abstract Selection of significant genes via expression patterns is important in a microarray problem. Owing to small sample size and large number of ...
Genome-wide transcriptional profiling has important applications in evolutionary biology for assaying the extent of heterozygosity for alleles showing quantitative variation in gene expression in ...
Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...