Neurodegenerative diseases (NDDs) represent a profound challenge to global health, characterized by progressive neuronal dysfunction and loss, leading to ...
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer’s disease and preserves cognitive function ...
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Replacing large mouse gene regions with human DNA
Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...
Understanding human gene function in living organisms has long been hampered by fundamental differences between species.
Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...
About 1 million Americans suffer from Parkinson's disease, with around 90,000 new cases diagnosed each year, according to the ...
Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...
"It is a Digital Twin model of human, which implements an AI model and it is trained on various human parameters that lead to ...
Exploring the role of FXYD family (FXYD domain-containing ion transport regulators) proteins in health and disease The FXYD ...
Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...
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