In the gastrointestinal tract, intraepithelial lymphocytes are tasked with protecting the epithelium against pathogens and participating in wound repair and correct mucosal barrier functioning. In a ...

Science X is a network of high quality websites with most complete and comprehensive daily coverage of the full sweep of science, technology, and medicine news ...

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In ...

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH ...

Nope, this isn’t a small, prickly mammal with a flashy dye job, but a single intestinal epithelial cell. The colorful, hairlike structures are microvilli, which are designed to maximize the cell’s ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

FPR2 activation regulates ISC proliferation and differentiation by activating the Wnt, Notch, and Hippo pathways via the PKC-ERK signaling axis. The intestinal epithelium undergoes rapid renewal every ...

The research projects in Michael Snyder, PhD’s lab at Stanford cover a wide range of interests; COVID-19, the NASA twin study, and personal omics profiling to name some examples. Another interest of ...

mTOR, mammalian target of rapamycin; p70S6K, The 70kDa ribosomal S6 kinase 1; NLRP3, NOD-like receptor thermal protein domain associated protein 3; ASC, apoptosis-associated speck-like protein ...