Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method ...

Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

UPTON, NY - Scientists have long thought that individual enzymes have specific, single jobs dependent on their molecular shape. According to this premise, enzymes could only evolve to perform new ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Malathy Palayam, Aleczander Young, Lior Tal, and Nitzan Shabek at the UC Davis Department of Plant Biology are exploring the mechanism by which the plant hormone strigoractone regulates a massive ...

Dr. Ahmed Lawan, an assistant professor in the College of Science at The University of Alabama in Huntsville (UAH), a part of The University of Alabama System, has published a paper in the journal ...

Patients with lupus are at increased risk of heart disease. Exposing endothelial cells -- known to protect against heart disease, in part by producing nitric oxide -- to the serum of patients with ...

Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

Researchers at Baylor College of Medicine and collaborating institutions report in the journal Nature Communications how a mutation in the enzyme SKD3 can cause a form of a genetic disease known as ...