A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Researchers devised a reversibly lockable DNA device for enclosing an enzyme and controlling its access to substrates. Turning on and off the activity of a single enzyme on demand is a much desired ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their energy-generating powerhouses, the mitochondria. The study illustrates how a ...

Many medications and other therapeutic agents, including antibiotics and cancer therapies, must enter cells to reach their ...

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key ...

Amides and thioesters are ubiquitous compounds in chemistry, used for the production of medicines, natural products, and advanced materials. Traditionally, their synthesis is a messy business, ...