A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Researchers devised a reversibly lockable DNA device for enclosing an enzyme and controlling its access to substrates. Turning on and off the activity of a single enzyme on demand is a much desired ...

Many medications and other therapeutic agents, including antibiotics and cancer therapies, must enter cells to reach their ...

New research identifies several existing compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory. The inhibitors all demonstrated potent chemical ...

Amides and thioesters are ubiquitous compounds in chemistry, used for the production of medicines, natural products, and advanced materials. Traditionally, their synthesis is a messy business, ...

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key ...