A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a single-step technique for ...
In Ed Boyden’s laboratory, new students and postdocs are issued with the essential kit of their trade: micropipettes, a notebook, a computer — and a flashlight. From bicycle beacons to camping lamps, ...
A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before ...
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A brief history of expansion microscopy
Nearly 150 years ago, scientists began to imagine how information might flow through the brain based on the shapes of neurons they had seen under the microscopes of the time. With today's imaging ...
Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.
Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy. The advancements could help provide future insight into ...
Understanding how muscles grow is the key difference between training hard and training effectively. Muscle hypertrophy is ...
Researchers have developed a novel bioink that uses a sustained-release hormone to promote the growth and regeneration of 3D-printed muscle tissues. Their approach opens the door to developing new ...
Expansion microscopy (ExM) is a route to bioimaging in which a crosslinked swellable hydrogel is used to physically expand fluorescently labelled tissues without disturbing the cellular structure.
A new variant of expansion microscopy that is tailored for brain pathology samples reveals cells and structures that can’t be seen with other methods. Expansion microscopy is a way of achieving the ...
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