A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

Chung’s group captured the transition period directly by improving the time resolution of a method called single-molecule ...

FCS provides critical advantages in proteomics, enabling non-destructive analysis of molecular dynamics and protein interactions in live environments.

Crystal jellyfish have an eerie beauty: thanks to a natural protein, they emit a faint green glow. For decades, researchers have used that green fluorescent protein and similar molecules to light up ...

Fluorescent dyes are tools used throughout biotechnology and medicine that offer a unique method of detecting and quantifying the presence of a target molecule, cell, or tissue within an even more ...

A common biological surface analysis technique breaks proteins up into smaller molecules that look identical. Reference spectra can help analyze these proteins for understanding diseases and creating ...

A proteomics data pipeline transforms raw mass spectrometry spectra into biologically interpretable protein-level ...

A major step forward toward biosensor devices that can provide fast, high-contrast detection of biomarkers in almost any environment are 'binding-activated fluorescent biosensors.' Now, a research ...

The copper target was operated at voltages of 11 kV, 12 kV, 13 kV, and 14 kV for the electron source, and a 50 kV configuration using a molybdenum target was used as a representative example for the ...

Force spectroscopy relies on the precise measurement of forces acting on a probe as it interacts with a sample. The key principles of force spectroscopy include: AFM-based force spectroscopy is the ...