The secretory pathway in eukaryotic cells is crucial for maintaining cellular function and physiological activities, as it ...

ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane ...

The Living Brain Project (LBP) is a collaborative research initiative led by the Icahn School of Medicine at Mount Sinai. Its mission is to generate, analyze, and openly share the world’s first ...

Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial ...

A University of Alberta research team is shedding much-needed light on cancer cachexia, a severe muscle-wasting syndrome ...

The microbes in the human gastrointestinal tract can have a significant influence on human health and disease, and this gut microbiome has been associated with a wide array of characteristics and ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

Biochemistry is the study of the chemicals and chemistry of living organisms. Biochemists study biomolecules (such as proteins, RNA, DNA, sugars, and lipids), their applications and interactions in ...

A new study highlights just how flexible the human body can be by demonstrating that in adult transgender women receiving ...