About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane ...
A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...
Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...
About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane receptors called G ...
Researchers used GPS-like tracking to observe how a key G protein-coupled receptor (GPCR) moves, revealing the core mechanism behind vital body functions. G protein-coupled receptors are embedded in ...
AbbVie is paying $255 million cash to acquire British biotech DJS Antibodies and its platform for targeting transmembrane proteins. DJS is focused on difficult-to-drug disease-causing proteins, such ...
SAN DIEGO--(BUSINESS WIRE)--Escient Pharmaceuticals, Inc., an industry-leading company developing Mas-related G Protein-Coupled Receptor (MRGPR)-targeted drugs to address serious, underserved medical ...
We are working on medicines* to fulfill unmet needs. We believe that small-molecule therapies targeting G-protein-coupled receptors (GPCRs) have the potential to transform the lives of patients with ...
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Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions
Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University ...
A publication from Acta Pharmaceutica Sinica B discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a debilitating ...
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