Heregulin as a novel cetuximab-resistace factor in colorectal cancer. Background: Hypoxia-inducible factor-1 (HIF-1) is the key regulator of cellular response to hypoxia and presumably plays a central ...

Synthetically Optimized HIF-1 Alpha DNA Delivered with Inovio's Electroporation Technology Provides Significant Therapeutic Effects for Peripheral Arterial Disease in Animal Model New application of ...

Hypoxia-inducible factor 1 (HIF-1) attenuates amyloid-beta protein neurotoxicity and decreases apoptosis induced by oxidative stress or hypoxia in cortical neurons. Prof. Xiqing Chai and co-workers ...

Low oxygen levels in the cellular environment are known to trigger the hypoxic response pathway. Hypoxia-inducible transcription factor, or HIF for short, is fundamental to the hypoxic response. HIF ...

Ileana Ruxandra Botusan, Vivekananda Gupta Sunkari, Octavian Savu, Anca Irinel Catrina, Jacob Grünler, Stina Lindberg, Teresa Pereira, Seppo Ylä-Herttuala, Lorenz Poellinger, Kerstin Brismar, ...

Enzon Receives FDA Clearance of HIF-1 alpha Investigational New Drug Application BRIDGEWATER, N.J -- Jan 25, 2007 - Enzon Pharmaceuticals, Inc. today announced that the U.S. Food and Drug ...

Role of quantitative gene expression using RT-PCR in the prediction of recurrence risk in resected T1 clear cell renal cell carcinoma (ccRCC). Background: Antiangiogenic agents are used to treat ...

Individuals with a condition known as Chuvash polycythemia, which is caused by a specific mutation in the protein VHL, have a greater proportion of their blood volume occupied by red blood cells than ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Back to Healio On February 12, the FDA accepted its ...

A certain biological pathway drives the inflammation seen in the skin disease psoriasis. A certain biological pathway, a set of linked reactions in the body, drives the inflammation seen in the skin ...