SLAMF8 as a potential therapeutic target for modulating tumor-associated macrophages in colorectal cancer. Inhaled KB707, a novel HSV-based immunotherapy, as a monotherapy in patients with advanced ...

Cytogenetic responses to the hypomethylating agent, decitabine (DAC), in a phase III trial of DAC vs supportive care (SC) in patients (pts) with myelodysplastic syndromes (MDS) No significant ...

BOSTON—In people with Alzheimer’s disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain. Evidence ...

Therapeutics for peripheral neuropathies, such as Charcot-Marie-Tooth (CMT) disease, are still quite limited and focus on managing symptoms. Augustine Therapeutics NV has presented an orally available ...

Heart failure with preserved ejection fraction (HFpEF) has limited treatment options and remains a medical challenge. HFpEF is characterized by diastolic dysfunction with a normal ejection fraction.