The American Journal of Managed Care

Importance of Early Identification and Diagnosis of HoFH

Early testing for HoFH may lead to significant improvement in patient prognosis. Seth Baum, MD: Diagnosing homozygous FH [familial hypercholesterolemia] is a little difficult, as is diagnosing ...
EurekAlert!

Optimized LbCas12a variant efficiently generates homozygous or biallelic mutations in Arabidopsis grown at 22 °C in a single generation

This study is led by Professor Qi-Jun Chen (State Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing 100193, China). The authors ...
Nasdaq

Esperion Aligns with U.S. Food and Drug Administration to Initiate Phase 3 Clinical Trials of Bempedoic Acid in Pediatric Heterozygous and Homozygous Familial Hypercholesterolemia

– Confirms Sufficient Data to Complete Phase 2 Clinical Study Enrollment and Advance to Phase 3 Studies in Both Heterozygous and Homozygous Familial Hypercholesterolemia – – Establishes Pediatric Path ...
ascopubs.org

Heterozygous Germline Fanconi Anemia–Related Gene Mutations Increase Susceptibility to Germ Cell Tumors

Germ cell tumors (GCTs) are a heterogeneous group of neoplasms that predominantly affect adolescents and young adults. Notably, geographical disparities in GCT incidence exist, with higher rates ...