For Dr. Daniel Gilada, a husband, physician and soon-to-be father of four, living with Type 1 diabetes had become “overwhelming.” “I felt so bad that it was becoming my new norm,” said Gilada, ...

For the first time, researchers have transplanted gene-edited donor islet cells that secrete insulin in a person with type 1 diabetes (T1D) without the use of immunosuppression. The study subject, a ...

An investigational antibody could reduce the toxicity associated with immune suppression in islet cell transplantation for type 1 diabetes (T1D), according to new preliminary data. Six people with T1D ...

Uppsala University Hospital-led investigators report that gene-edited donor islet cells survived 12 weeks inside a man with long-standing type 1 diabetes without any immunosuppressive medication.

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells ...

Forbes contributors publish independent expert analyses and insights. For decades, the ambitious goal of regenerative medicine has been to replace damaged or lost tissues with healthy, functioning ...

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimislecel ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies. Researchers led by ...

A vascularized organoid model of hormone-secreting cells in the pancreas has been developed, with potential to improve diabetes research and cell-based therapies. “Our results highlight the importance ...

Islet Transplantation with Blood Vessel Cells Shows Promise to Treat Type 1 Diabetes Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the ...