Pharmeceutical companies could soon have easier access to synthetic alternatives to horseshoe crab blood, a key ingredient used to test vaccines and medical devices for contamination. The U.S.

Horseshoe crab blood is highly valuable because it contains a unique substance called Limulus Amebocyte Lysate (LAL), which is used in a test to detect bacterial endotoxins. This test, known as the ...

Believe it or not, horseshoe crabs help ensure the safety of pharmaceuticals and save human lives. There is a chemical, Limulus Amoebocyte Lysate (LAL), derived from horseshoe crab blood that ...

Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

A chemical compound found in the blood of horseshoe crabs is widely used in the biomedical community to test for the presence of bacterial exposure or infection. This limulus amebocyte lysate (LAL) ...

As thoroughly covered in your recent article (C&EN, Oct. 28, 2024, page 26), the issue of replacing the traditional natural product test for endotoxin, limulus amoebocyte lysate (LAL), with a ...

With the introduction of pioneering technology for bacterial endotoxins testing (BET), it is critical to demonstrate equivalency across platforms. The Sievers Eclipse Ratio Verification Test was ...

Believe it or not, horseshoe crabs help ensure the safety of pharmaceuticals and save human lives. There is a chemical, Limulus Amoebocyte Lysate (LAL), derived from horseshoe crab blood that ...