CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

The latest biotech industry insights, from ELRIG’s newest work group leaders to the launch of a platform for amplifying DNA methylation.

A genome-wide cfDNA methylation enrichment method (cfMeDIP-seq) enables response monitoring using plasma alone, avoiding ...

The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

CDCA7 binds to the hemimethylation site in the major groove of nucleosomal DNA without base-flipping. R274 confers preferential binding of CDCA7 to a hemimethylated CpG. The side chain of Q275 is ...

A team of Mayo Clinic researchers has succeeded in identifying the source of cancer in patients' gastrointestinal tracts by analyzing DNA markers from tumors. The results open the possibility that ...

A proprietary mcPCR platform allows high-fidelity amplification of DNA methylation and genetic sequences together. The advance supports precise clinical testing, earlier diagnosis, and improved ...

In a recent study published in The Lancet Planetary Health, researchers evaluated the relationship between prenatal air pollutant exposure concentrations and changes in placental deoxyribonucleic acid ...