Sarcomas, a diverse group of malignancies, exhibit substantial heterogeneity in both biological behavior and microenvironment, influencing their response to immunotherapy. Although pembrolizumab is ...

A next-generation sequencing (NGS)–based technique was used for MSI analysis in 4,553 patients with various tumor types. Upon request, somatic BRAF gene analysis was conducted. In addition, hereditary ...

Merck & Co. has tapped the artificial intelligence developer Owkin to help assemble a new slate of digital diagnostics for cancer testing. The collaboration will expand upon Owkin’s machine ...

CHICAGO--(BUSINESS WIRE)--Cellworks Group Inc., a leader in Personalized Therapy Decision Support and Best-in-Class PTRS, today announced compelling results from a new study demonstrating the ability ...

A new microsatellite instability (MSI) system by Promega, the LMR MSI Analysis System, enables cancer researchers a broader view of mismatch repair deficiency (dMMR). An expanded set of MSI markers ...

Compared with chemotherapy, immune checkpoint inhibitors (ICIs) were associated with improved overall survival in patients with microsatellite instable metastatic colorectal cancer (CRC), particularly ...

Werner syndrome ATP-dependent helicase (WRN) is an enzyme involved in DNA replication and repair and has been identified as a synthetic lethality target in tumors with high microsatellite instability ...

Please provide your email address to receive an email when new articles are posted on . In this video, Arvind N. Dasari, MD, MS, discussed the results of the CheckMate 8HW trial in which nivolumab and ...