Application of CAPTURE Assay for Early Diagnosis and Prognosis in Bile and Blood of Cholangiocarcinoma In 467 consecutive patients with ALL (0-20 years), we compared RNA sequencing (RNAseq), ...

Circular RNA (circRNA) is a unique type of non-coding RNA produced by back splicing of mRNA to form the covalent junction without 3’-5’ polarity and poly(A) tail. CircRNA was first discovered about 30 ...

Understanding molecular diversity is fundamental to biomedical research and diagnostics, but existing analytical tools ...

In vitro diagnostics (IVD) is an umbrella term for tests conducted on blood or tissue samples to detect diseases, determine the efficacy of novel or established treatments, and monitor health.

Just about any scientist would say that creating a novel and reproducible method that provides accurate, unambiguous results is a difficult path. Magnify the difficulty with the added task that the ...

Parkinson's disease is often not diagnosed until later stages, when many nerve cells in the brain have already died off, and movement problems have started. This means that many people don't start ...

The most common methods being used to detect circRNA are RNA sequencing and RT-PCR. “RNA sequencing can reveal the actual structure and discover new circRNA, but it is inefficient and hence tends to ...