The Indianapolis Colts and the Green Bay Packers face off in Week 2 of the NFL preseason today. Here's where to watch and start time.

Watch highlights from the Week 2 matchup between the Green Bay Packers and Washington Commanders on Thursday, Sept. 11, 2025, at Lambeau Field.

Green Bay Packers vs Washington Commanders picks, predictions, win probabilities for NFL Week 2 Thursday Night Football game Sept. 11. Who will win?

Highlights from the Week 1 matchup between the Miami Dolphins and the Indianapolis Colts during the 2025 NFL season.

Florio’s pick: Cowboys 23, Giants 13. Simms’s pick: Cowboys 28, Giants 17. From 15-2 in the 2024 regular season to 0-2 between the 2024 postseason and Week 1. The Lions are experiencing the growing pains of a team that is learning how to be a winner.

Some of the site's predictions differ from NFL Week 2 odds and other NFL Week 2 picks for NFL Week 2 games. How correct will the analytics be this week? Click on each game for more NFL Week 2 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

Our NFL handicapping trio of Corbie Craig, Ed Feng and Michael Fiddle combine to give their best bets for Week 2 of the NFL season. This file will be updated throughout the weekend. Odds courtesy of BetMGM.