Targeted next-generation sequencing (NGS) is often performed using hybridization-based target enrichment, which deploys oligonucleotide probes to capture regions of interest for downstream sequencing.

A new spatial transcriptomics technology—the DNA nanotechnology-driven method called “Light-Seq”—allows researchers to “geotag” the full repertoire of RNA sequences with unique DNA barcodes exclusive ...

Researchers at Boston Children's Hospital said they sequenced a patient's genome in 3 hours and 57 minutes, breaking a Guinness World Record in the process.

Early detection of cancer using cell-free DNA (cfDNA) size analysis on a multiplexed amplicon-based next-generation sequencing (NGS) platform. Systemic levels of the soluble co-inhibitory immune ...

The discipline of genomics has experienced an unprecedented revolution, boosting the understanding of health and illness and promoting the creation of customized medicine for better therapeutic ...

Complicated molecular alterations in tumors generate various mutant peptides. Some of these mutant peptides can be presented to the cell surface and then elicit immune responses, and such mutant ...

Investigators examined the current bodies of evidence surrounding the emergence of next-generation gene sequencing, and the challenges that come with it, for identifying oncogenic drivers of ...