That overwhelming sleepiness dragging you down might not just be from staying up too late scrolling through TikTok. While everyone occasionally battles the afternoon slump, people with hypersomnia or ...

When Katelynn O’Connell takes her lunch break at work, she follows a routine that sets her apart from other employees. Each day at noon, she unfolds a cot in her small office, turns on a white noise ...

If you're often exhausted and don't have enough energy to make it through the day, you might ask yourself: Am I sleep-deprived, or am I dealing with a more serious medical condition? Multiple sleep ...

There is no biological measure for wakefulness. In a narcolepsy clinical trial, a patient lies down in a dark lab while clinicians count the minutes until sleep comes. The average time in four tests ...

Elaine Chen covers biotech, co-writes The Readout newsletter, and co-hosts STAT’s weekly biotech podcast, The Readout Loud. You can reach Elaine on Signal at elaineywchen.70. Alkermes and Takeda ...

A hormone produced by the brain, orexin, may play a central role in the functioning of the brain’s glymphatic system, which clears waste, according to a new study from the University of Oulu.

Takeda and Alkermes both took data from their orexin receptor 2 (OX2R)-selective agonists to Singapore this morning as the race to get a new class of narcolepsy drugs approved heats up. Takeda ...

Risk for cardiovascular disease was significantly increased in patients with narcolepsy, highlighting the importance of routine screening in this population. Patients with narcolepsy have a ...

Takeda is on track to submit its much-hyped narcolepsy drug to regulators this fiscal year after the orexin receptor 2 (OX2R)-selective agonist scored a pair of phase 3 wins. The Japanese pharma had ...