The interior of a cell is packed with proteins and nucleic acids, such as RNA, all of which need to perform specific ...

Before a new medication arrives on the market, it must be tested on animal models and in humans. In order to conduct these tests, a substantial amount of the therapeutically effective substances are ...

A significant step has been made toward visualizing small biomolecules inside living biological systems with minimum disturbance, a longstanding goal in the scientific community. In a study, a ...

Synchrotron X-ray footprinting is a valuable method to observe the structure and dynamics of biological macromolecules and their interactions with each other, as well as with smaller molecules such as ...

Supersensitive detection systems are an important element of today's life sciences. Their development aims to achieve utmost sensitivity and smallest possible sample consumption in detecting and ...

In the late 1960s, Bonucci and Anderson first reported finding small, secreted extracellular vesicles in bone cells. Over the next 20 years, through the combined use of electron microscopy, ...

It is surely time for water to take up its rightful position as the most important and active of all biological molecules, and leave behind the perception that its influence is inconsequential and its ...

Anti-nucleolin DNA aptamer, iSN04, inhibits angiogenesis. Mouse aortic rings embedded in collagen gel were cultured with or without 30 µM iSN04 for 6 days. Neovascular sprouting, a model of ...