The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...

A new class of CRISPR-based tools efficiently corrects point mutations in cell lines, animal models and perhaps the clinic. When Xingxu Huang began thinking about correcting disease-causing mutations ...

In a global first, scientists have used advanced base editing to repair a deadly gene mutation in a newborn, marking a major leap forward in the treatment of rare ...

Scientists have discovered a new way by which DNA repairs itself, a process that is critical to the protection of the genome, and integral to prevention of cancer development. A team of researchers at ...

Zettabytes—that’s 10 21 bytes—of data are currently generated every year. All of those cat videos have to be stored somewhere, and DNA is a great storage medium; it has amazing data density and is ...

Nucleotides are the building blocks of the two nucleic acids, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). As such, they are also the building blocks of you and every other lifeform on ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.

Genome editing holds promise for correcting pathogenic mutations. However, it is difficult to determine off-target effects of editing due to single-nucleotide polymorphism in individuals. Here we ...