The authors set out to answer a simple question. Do all chromosomes have the same chance of being mis-segregated during cell division? To address this, Klaasen and colleagues turned to several types ...

Inside each of your cells lies a nucleus, its master command center. Protected inside each nucleus are your chromosomes, ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

This important study demonstrates that a peri-nuclear actomyosin network, present in some types of human cells, facilitates kinetochore-spindle attachment of chromosomes in unfavorable locations - ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Nucleosomes (blue sphares) in active chromatin regions form condensed domains with local nucleosome contacts and cohesin (rings), where nucleosomes fluctuate. Each interphase chromosome (highlighted ...

Whether at the start of a sinus infection or a fresh open wound, neutrophils are the first line of defense in an immune attack. 1 In order to rush to the scene to kill infectious microbes, they have a ...

Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus. His research could lead to new treatments for cancer and viral diseases.

Researchers from Carnegie Mellon University's School of Computer Science have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge ...