Cells are characterized to be stable yet highly flexible. They constantly modify their shape and even move through tissue. These vital properties are based on a dynamically organized network of ...

The Fowler laboratory studies cellular architecture: how cells spatially organize themselves and their interior compartments to achieve intricate geometries, mechanical strength, and physiological ...

Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics. Steroid hormones, to which belong sex hormones like estrogen or ...

Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to ...

Actin and myosin are components of the plant cell cytoskeleton that extend from cell to cell through plasmodesmata (PD), but it is unclear how they are organized within the cytoplasmic sleeve or how ...

Most cell structures are not visible to the naked eye without using stains for visualization. The stains used in these images highlight how cell biologists use tricks to “see the invisible.” Invite ...

Researcher are now able to rebuild the switch that remodel the cytoskeleton. Images of an anaphase cytoskeleton in a dividing cell (left) and when rebuilt in vitro (right). PRC1 (green) crosslinks ...

Oosterheert W, Sanders MB, Hofnagel O, Bieling P, Raunser S. Choreography of rapid actin filament disassembly by coronin, cofilin and AIP1. Cell https://doi.org/10.1016/j.cell.2025.09.016 ...