About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

Nanopore sensors enable precise protein and peptide analysis, crucial for early disease diagnosis and advancing personalized ...

Illustration showing how integrating protein three-dimensional structures with artificial intelligence algorithms can predict synergistic or antagonistic effects of drug combinations, guiding safer ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

The sensory receptor PIEZO1 changes shape in response to mechanical stimuli. The super high-resolution microscopy technology used in this discovery is a breakthrough in enabling protein structures to ...

How does skin hold you in? How do heart cells beat together? Researchers at the University of California, Davis, Department ...

Rourkela have uncovered how natural sugar-like molecules in the human body can alter the behaviour of a protein responsible ...

A new study reveals how targeted electromagnetic waves can disrupt the SARS-CoV-2 spike protein, potentially opening doors to innovative disinfection and infection control strategies. Study: ...