Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...

Using a high-throughput fluorescence microscopy system and machine learning algorithms, oxidative stress-related changes in protein localization have been mapped by researchers from Japan. Furthermore ...

CAMBRIDGE, MA – A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer’s, cystic fibrosis, and cancer. But there are about 70,000 different proteins and ...

An international team has assembled the first large-scale, publicly available map to show the impact of mutations on where proteins end up in the cell. The team developed a high-throughput imaging ...

Spatial proteomics is the study of the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular function, making spatial ...

The team developed a high-throughput imaging platform to assess the influence of nearly 3,500 mutations on protein location. They found that roughly one in six disease-causing mutations led to ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

Scientists discovered a role played by ribosomes during the folding of new proteins in cells. Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...