The treatments prioritized in a phase II trial are then tested definitively against a control treatment in a randomized phase III trial. Randomized phase II/III trials use an adaptive trial design ...

The authors sought to understand the differential impact of payer-led community-based care management approaches on stakeholder-oriented outcomes for publicly insured adults with multiple chronic ...

Randomized clinical trials remain the gold standard for establishing a medication's effects, producing the evidence by which ...

There are no established treatment options for patients with meningioma recurring after surgery and radiotherapy.

Background While female sex has historically been associated with worse outcomes following surgical aortic valve replacement, ...

Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic ...

Medical research is essential for advancing the understanding of health, diseases, and treatments. There are many types of studies that serve different purposes. Medical research, or health research, ...

Large language models could transform digestive disorder management, but further RCTs are essential to validate their ...

Regeneron Pharmaceuticals ($REGN) announced an update on their ongoing clinical study. Study OverviewRegeneron Pharmaceuticals has launched a new ...