A powerful new drug combination—niraparib added to standard prostate cancer therapy—has been shown to significantly delay ...

A targeted drug combination delays advanced prostate cancer in men with specific DNA repair gene mutations. A large international study led by researchers at UCL has found that a new combination of dr ...

Adding PARP inhibitor niraparib to standard prostate cancer treatment delays disease progression in men with certain DNA ...

Identification of variants influences treatment decisions. Inhibitors of the poly-ADP-ribose polymerase (PARP) system, a pathway for repairing single-stranded DNA breaks, are recommended for tumors ...

Naked mole rat's unique DNA repair mechanism may hold key to longevity and age-related research breakthroughs.

Naked mole-rats seem to have found nature’s cheat code for longevity. Scientists discovered that small tweaks in one of their ...

These burrowing animals have a biological mechanism that does the opposite of what it does in humans: it repairs DNA instead ...

A study reveals the secrets behind the rodent’s remarkable ability to live 10 times longer than expected, without cancer or ...