A new chapter is unfolding for gene therapies in Europe. With retinal programs advancing into Phase I/II trials and regulators introducing more flexible approval pathways for rare diseases, the field ...

After teasing a new regulatory process for personalized genetic medicines at the end of last year, the FDA today unveiled draft guidance for an approval pathway that could see custom CRISPR therapies, ...

Medaka fish that lacked functional Hmgn2 genes were unable to distinguish between simple shapes, revealing a new function for the regulatory gene. Medaka fish that lacked functional Hmgn2 genes were ...

KYOTO – An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. A new study has comprehensively analyzed ...

Gene regulation is far more predictable than previously believed, scientists conclude after developing the deep learning model PARM. This might bring an end to a scientific mystery: how genes know ...

Transposable elements (TEs) are repetitive DNA sequences that originate from ancient viruses and currently make up nearly half of the human genome. While TEs were once labeled as “junk” DNA with no ...

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

Plant breeding has contributed to the sustainability of crop production since antiquity and is expected to play an increasingly important role in the ...

DNA is the blueprint of life. Genes encode proteins and serve as the body’s basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...