The interior of a cell is packed with proteins and nucleic acids, such as RNA, all of which need to perform specific ...

A groundbreaking study reveals that human cells initiate self-destruction processes when viruses disrupt RNA production, ...

RNA-based vaccines were the heroes of the COVID-19 pandemic. They set records for the highest-grossing drug launches in history, and their development was recognized in this year’s Nobel Prize in ...

The W.M. Keck Foundation awarded a $1.2 million grant to medicinal chemistry and computational biology researchers at the University of Kansas (KU) and the University of Chicago focused on finding ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell ...

They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes blister-like skin rashes, and influenza viruses ...

This article is part 2 of a series on next-generation mRNA vaccines. The first installment can be read here. The unprecedented speed with which we developed vaccines to help us control and curb the ...

Scientists have created a model to study the role of RNA splicing defects in Alzheimer's disease, revealing degeneration and toxicity caused by neuron hyperexcitability. Researchers have puzzled over ...

A wide spectrum of cancer-associated genetic alterations, including those that result in changes to the splicing of pre–messenger RNA (mRNA), can lead to the presentation of aberrant peptides as ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this ...