When neuroscientists analyzed the exact properties of nerve connections in the brain, they made a startling observation: At a key connection, or synapse, messages are sent against the usual stream of ...

Nervous system functions, from motion to perception to cognition, depend on the active zones of neural circuit connections ...

The synaptotagmin protein family has been studied by neuroscientists for decades. However, most isoforms lack well-defined functions. Now, researchers have identified a crucial, presynaptic role for ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...