A research team has resolved a 50-year-old controversy in neuroscience. By employing a self-developed, time-resolved ...

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

Researchers have long believed that neurons rely on glucose nearly entirely for fuel. The brain’s enormous energy ...

In a study published in Science on October 17, a team led by Prof. BI Guoqiang from the University of Science and Technology of China/Shenzhen ...

In A, researchers used a fluorescent protein (synaptopHluorin) to visualize synaptic vesicle movement. Some vesicles stay open briefly before retrieval (kiss-and-run). Others stay open longer but also ...

We study the genetic pathways that enable neurons to reliably signal to other cells. Neural signaling depends on the controlled, activity-dependent release of neurotransmitters. These hormone-like ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Video depiction of vesicle fusion and tethering. In the active zone in the central left of the video, docked vesicles (dark blue) fuse with the membrane, releasing their contents and being quickly ...

Max Delbrück Center for Molecular Medicine in the Helmholtz Association Researchers led by Uljana Kravčenko and her colleagues in the lab of Professor Misha Kudryashev, Group Leader of the In Situ ...