I have about 100 GB of 16 bit grayscale TIFFs I need to back up. Is there anything I can use to reduce the size without losing any of the quality (pictures are from my research so I can't lose quality ...
The next time you start pining for the good old days of computing, keep this in mind: In 1995 we had to negotiate hundreds of image file formats, and no two imaging programs spoke the same language.