The three eukaryotic DNA-dependent RNA polymerases (Pol) — the nucleoplasmic Pol II and Pol III and the nucleolar Pol I — were isolated 50 years ago. To celebrate this anniversary, Nature Reviews ...

A research team introduces a new large-scale study on human transcription factors combining two state-of-the art interactomics methods that allow rapid identification of protein-protein interactions ...

DNA, the long polymer curled up inside our cells, is often described as the instructions for life. But those instructions are stored in DNA’s chemical code, and reading that code requires the ...

In Eukarya, RNA Polymerase II (Pol II) transcription is a highly regulated process, which is responsible for the transcription of all protein encoding genes. While the catalytic core of the Pol II ...

In a surprising discovery, MIT scientists found tiny loops in the genomes of dividing cells. Enabled by a high-resolution ...

Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...

High soil salinity disrupts water absorption, ion balance, and photosynthesis in plants, leading to growth inhibition and ...

Expression analysis of ClLEA55, phenotypic and physiological analysis of ClLEA55 knockout lines under 300 mM NaCl treatment ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...