tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

In 1965, Cornell biochemist Robert Holley deciphered the 77 nucleotide sequence of transfer RNA. Three years later, Holley was awarded the Nobel Prize for this work, but already the race to determine ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the development of a new method for simultaneously synthesizing all transfer RNA (tRNA) ...

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Life may have first emerged in deep sea thermal vents or surface hot springs (Yellowstone National Park’s Grand Prismatic Spring is shown here). New research shows how high-energy thioesters could ...

Scientists have developed a fast, non-invasive blood test that can detect Parkinson’s disease before tremors begin. By measuring RNA fragments that reflect brain pathology, the test offers new hope ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...